CAM and NK Cells

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CAM and NK Cells

It is believed that tumor development, outgrowth and metastasis are under the surveillance of the immune system. Although both innate and acquired immune systems play roles, innate immunity is the spearhead against tumors. Recent studies have revealed the critical role of natural killer (NK) cells in immune surveillance and that NK cell activity is considerably influenced by various agents, suc...

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Commentary on CAM and NK Cells by Kazuyoshi Takeda and Ko Okumura

© Oxford University Press 2004 *Professor and Editor-in-Chief, Tel: (310) 825–9567; Fax: (310) 825–2224. E-mail: [email protected] anticipatory, clonal and somatic. Each of these terms defines Professor and Editor-in-Chief, Laboratory of Comparative Neuroimmunology, Department of Neurobiology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California 90095–17...

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It is no exaggeration that stem cells are a hot topic in the international biomedical arena. In California we are particularly and actually aware of this fact. We started the new year on January 12 with a Stem Cell Technology Conference focusing on senescence. More than a year after California voters elected to give $3 billion in bonds to fund stem cell research, and with the measure stalled in...

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CD26+ Cord Blood Mononuclear Cells Significantly Produce B, T, and NK Cells

Background: Umbilical cord blood (UCB) is an alternative source of hematopoietic stem cell transplantation (HSCT), used in Leukemia treatment. CD26+ cells, a fraction of CD34 positive cells, are a major population of UCB cells which negatively regulate the in vivo homing and engraftment of HSCs. CD26 is highly expressed in various cells such as HSCs, immune cells, fibroblasts, and epithelial ce...

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Activating natural killer (NK) cytotoxicity of canine CD5−CD21− cells requires low surface CD5 density NK cells

Natural killer (NK) cells play a crucial role in regulating immune functions. Few studies have characterized canine NK cells. We previously demonstrated that canine peripheral blood lymphocytes (PBLs) with a low surface CD5 density (CD5lo) are considered a critical NK population. Natural killer cells in most mammals do not express T-cell markers, but canine CD5lo cells express surface molecules...

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ژورنال

عنوان ژورنال: Evidence-Based Complementary and Alternative Medicine

سال: 2004

ISSN: 1741-427X,1741-4288

DOI: 10.1093/ecam/neh014